Editorial: Small Non-coding RNAs in Streptococci

Editorial: Small Non-coding RNAs in Streptococci

Bacterial small RNAs (sRNAs) are post-transcriptional regulators of gene expression and the mechanisms by which this can occur have begun to be understood (Gottesman and Storz, 2011). In pathogenic bacteria, the importance of sRNAs-mediated regulation depends on a fine-tuning of the expression of various virulence genes (Papenfort and Vogel, 2010). For instance, RNAIII, a regulatory RNA from th...

Genome-wide analyses of small non-coding RNAs in streptococci

Streptococci represent a diverse group of Gram-positive bacteria, which colonize a wide range of hosts among animals and humans. Streptococcal species occur as commensal as well as pathogenic organisms. Many of the pathogenic species can cause severe, invasive infections in their hosts leading to a high morbidity and mortality. The consequence is a tremendous suffering on the part of men and li...

Editorial: Non-Coding RNAs in Neurodevelopmental Disorders

The Role of Long Non-Coding RNAs in Ovarian Cancer

Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. However, the aim of this review was to investigate the role of long non-co...

Small non-coding RNAs in Streptomyces coelicolor

In bacteria, small RNAs (sRNAs) make important regulatory contributions to an ever increasing number of cellular processes. To expand the repertoire of known sRNAs, we sought to identify novel sRNAs in the differentiating, multicellular bacterium Streptomyces coelicolor. We describe a combined bioinformatic and experimental approach that enabled the identification and characterization of nine n...